In the face of complex challenges, progress doesn’t stop. The 2025 Annual Report highlights our impact in combating HIV/AIDS and tuberculosis (TB) while building resilient, lasting health systems in South Sudan.

Under the leadership of the Ministry of Health—and in close collaboration with the South Sudan AIDS Commission, the Country Coordinating Mechanism, civil society, and frontline partners—this Global Fund-financed partnership continues to deliver life-saving services to the country’s most vulnerable and hard-to-reach areas.