This report presents the findings of the case for investing in tobacco control in Mozambique, a stated priority of the Government of Mozambique. In line with the WHO Framework Convention on Tobacco Control (WHO FCTC) Global Strategy to Accelerate Tobacco Control, it measures the costs and benefits – in health and economic terms – of implementing seven key WHO FCTC policy actions that focus on demand reduction. The seven actions are: 1) increase tobacco taxation to reduce the affordability of tobacco products (WHO FCTC Article 6); 2) create smoke-free public places and workplaces to protect people from the harms of tobacco smoke (WHO FCTC Article 8); 3) require graphic health warnings on tobacco product packaging that describes the harms of tobacco use (WHO FCTC Article 11); 4) implement plain packaging of tobacco products (WHO FCTC Guidelines for implementation of Article 11 and WHO FCTC Guidelines for implementation of Article 13); 5) promote and strengthen public awareness of tobacco control issues, including the health risks of tobacco use and tobacco smoke, addiction, and the benefits of cessation (WHO FCTC Article 12); 6) enact and enforce a comprehensive ban on all forms of tobacco advertising, promotion, and sponsorship (WHO FCTC Article 13); and 7) scale up of brief advice to quit for tobacco users in primary care clinics (WHO FCTC Article 14).