Digital scams pose a serious and growing threat globally, especially to vulnerable communities and developing countries. They represent a multifaceted “wicked problem” that requires a collective response. This Anti-Scam Handbook culminates from the work of UNDP and its coalition of experts across diverse sectors at the global and national levels. It addresses the gaps in global understanding on digital scams in developing countries; provides a toolkit to support countries in driving more effective multi-stakeholder collaborative responses; and presents case evidence across Africa, Asia Pacific, and Latin America.